Princess Mononoke

Princess Mononoke Japanese , Hepburn Mononokehime? , SpiritMonster Princess is a 1997 anime epic action historical fantasy film written and directed by Hayao Miyazaki. It was animated by Studio Ghibli and produced by Toshio Suzuki. The film stars the voices of Yji Matsuda, Yuriko Ishida, Yko Tanaka, Kaoru Kobayashi, Masahiko Nishimura, Tsunehiko Kamijo, Akihiro Miwa, Mitsuko Mori and Hisaya Morishige.

In Muromachi period Japan, an Emishi village is attacked by a demon. The last Emishi prince, Ashitaka, kills the demon before it reaches the village, but its corruption curses his arm in the battle. The curse gives him superhuman fighting abilities, but will eventually kill him. The villagers discover that the demon was once a boar god, Nago, corrupted by an iron ball lodged in his body. The villages wise woman tells Ashitaka that he may find a cure in the western lands Nago came from.Heading west, Ashitaka meets Jikob, a wandering monk, who tells Ashitaka he may find help from the Great Forest Spirit, a Kirinlike creature by day and a giant nightwalker by night. Nearby, men herd oxen to Irontown, led by Lady Eboshi, when they are attacked by a wolf clan led by the wolf goddess Moro. Riding one of the wolves is San, a human girl. Later, Ashitaka discovers two injured Irontown men, and sees San and her wolf clan he greets them, but they ignore him and leave. He carries the injured men through the forest, where he encounters many kodama, and glimpses the Forest Spirit. ........

Source: Wikipedia